Products
NOX4 antibody
- Product Name
- NOX4 antibody
- Catalogue No.
- FNab05806
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- NADPH oxidase 4
- Alternative Names
- Kidney oxidase 1 antibody, KOX antibody, KOX 1 antibody, NADPH oxidase 4 antibody, NOX4 antibody, Renal NAD(P)H oxidase antibody, RENOX antibody
- UniProt ID
- Q9NPH5
- Observed MW
- 60 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IP, IF, FC
- Recommended dilution
- WB: 1:200-1:2000; IP: 1:500-1:2000; IHC: 1:100-1:400; IF: 1:10-1:100
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab05806(NOX4 antibody) at dilution of 1:600
IP Result of anti-NOX4 (IP:FNab05806, 3ug; Detection:FNab05806 1:1000) with HEK-293 cells lysate 1700ug.
Immunohistochemistry of paraffin-embedded human kidney tissue slide using FNab05806(NOX4 Antibody) at dilution of 1:200
Immunofluorescent analysis of BxPC-3 cells using FNab05806 (NOX4 antibody) at dilution of 1:25 and Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG(H+L)
- Background
- Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB. May produce superoxide in the nucleus and play a role in regulating gene expression upon cell stimulation.
